Latest Advances in R&D on LNPs for RNA Drug Delivery

Zielsetzung

LNPs (Lipid Nanoparticles) have revolutionized the targeted
delivery of nucleic acid. Following their groundbreaking
role in COVID-19 vaccinations and hepatocyte-targeted
therapies (Onpattro®) as current product examples, the
field of LNPs is poised for further exploration. Academic
and industrial R&D are now facing the challenge to
further profit from and elaborate this breakthrough and
find new applications for the LNP technology. The course
addresses the latest progress made in the preclinical and
clinical R&D on these nanoparticles, including production,
stability, analytical and in-vivo delivery strategies. In addition,
the course informs on the increase of understanding of
the relation between LNP structure/composition and PK,
tissue distribution, efficacy and toxicity. Top experts in
this field from leading academic institutes and industry
will review these aspects in detail, share their knowledge
and findings, and provide a comprehensive overview of the
state-of-the-art and prospects in LNP research.